| 发明名称 |
Modulators of TNF-alpha signaling |
| 摘要 |
The present invention provides compounds which are modulators of TNF-alpha signaling and methods of use thereof for treating a patient having a TNF-alpha mediated condition. The compounds can be represented by the following structural formulas:
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| 申请公布号 |
US6969728(B2) |
申请公布日期 |
2005.11.29 |
| 申请号 |
US20010852965 |
申请日期 |
2001.05.10 |
| 申请人 |
GENZYME CORPORATION |
发明人 |
SNEDDON SCOTT F.;KANE JOHN L.;HIRTH BRADFORD H.;VINICK FRED;QIAO SHUANG;NAHILL SHARON R.;WILLIAMS JOHN M.;BIEMANN HANS-PETER |
| 分类号 |
C07D295/14;A61K31/277;A61K31/405;A61K31/417;A61K31/4178;A61K31/4439;A61K31/444;A61K31/498;A61K31/506;A61K31/53;A61K31/5375;A61K31/5377;A61P1/04;A61P1/16;A61P3/10;A61P5/14;A61P7/00;A61P7/02;A61P9/10;A61P9/14;A61P19/02;A61P21/04;A61P25/14;A61P25/28;A61P25/32;A61P29/00;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P31/18;A61P33/00;A61P35/00;A61P35/02;A61P37/02;A61P37/06;A61P43/00;C07C255/60;C07D233/54;C07D233/64;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D405/12;C07D409/12;(IPC1-7):C07C233/00;A61K38/05;A61K38/06;A61K38/07 |
主分类号 |
C07D295/14 |
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