发明名称 |
Phenylpiperazines with a combination of affinity for dopamine -D2 receptors and serotonin reuptake sites |
摘要 |
The invention relates to a group of novel phenylpiperazine derivatives with a dual mode of action: serotonin reuptake inhibition and affinity for dopamine -D2 receptors and to methods for the preparation of these compounds. The invention also relates to the use of a compound disclosed herein for the manufacture of a medicament giving a beneficial effect. The compounds have the general formula ( 1 ) wherein the symbols have the meanings given in the specification. |
申请公布号 |
AU2005313386(A1) |
申请公布日期 |
2006.06.15 |
申请号 |
AU20050313386 |
申请日期 |
2005.12.06 |
申请人 |
SOLVAY PHARMACEUTICALS B.V. |
发明人 |
PIETER SMID;ROELOF VAN HES;CORNELIS G. KRUSE;MARTINUS TH.M. TULP |
分类号 |
C07D319/18;A61K31/496;A61P25/28;C07D215/38;C07D265/36;C07D295/12;C07D307/82;C07D311/18;C07D321/10 |
主分类号 |
C07D319/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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