摘要 |
PROBLEM TO BE SOLVED: To provide a triazolopyridine compound as a PIM kinase inhibitor.SOLUTION: A compound of the formula I, where R, R, R, Rand Rhave meaning provided in the application, is a receptor tyrosine inhibitor useful in a treatment of diseases to which PIM-1 and/or PIM-2 and/or PIM-3. There is also provided a method for treating PIM-1 and/or PIM-2 and/or PIM-3 kinase mediated conditions in mammals including injecting the therapeutically effective amount of the compound of the formula I or a pharmaceutically acceptable salt into the mammals.SELECTED DRAWING: None |