摘要 |
PROBLEM TO BE SOLVED: To provide a cancer therapy.SOLUTION: The invention provides a method involving a composition containing a CDP-topoisomerase inhibitor, for example, CDP-camptothecin or a camptothecin derivative conjugate, for example, CRLX101. In one aspect, the present disclosure is characterized by therapies for proliferative diseases, for example, cancer in a subject. In one aspect, the present disclosure is characterized by therapies for lung cancer (for example, small cell lung cancer or non-small cell lung cancer (for example, adenocarcinoma, squamous cell carcinoma, bronchioloalveolar carcinoma, and large cell carcinoma)), for example, locally advanced and metastatic lung cancer in a subject, for example, a human subject.SELECTED DRAWING: Figure 1 |