发明名称 |
THERAPEUTIC AGENT FOR TREATING MENTAL DISEASE |
摘要 |
PURPOSE: To obtain a curing agent for human psychasthenia having high miscibility to aγ-receptor and useful for curing of a human neurological diseases by containing specific compounds. CONSTITUTION: This curing agent contains a pure optical isomer or a mixture of optical isomers in a free base state or a pharmaceutically allowable acid added salt state of a compound of the formula (R<1> is a halogen or hydroxy; R<2> is H or methyl; R<3> is H or a halogen) in an amount effective for anti- neurological diseases. As the compound of the formula, (±)erythro-α-(4- hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidine ethanol is exemplified. The compound of the formula is used in a formulation of tablet or capsule and within a range of 1-120mg of an active substance by combinedly using with a suitable excipient.
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申请公布号 |
JPH03170428(A) |
申请公布日期 |
1991.07.24 |
申请号 |
JP19900308425 |
申请日期 |
1990.11.13 |
申请人 |
SYNTHELABO SA |
发明人 |
SAROMON ZEDO RANJIE;JIYONATAN FUROSUTO;JIYOAN SUKEEMAKE;BERUNAARU GODEIRIEERU;JIYAN BERUTAN;JIYAN RUSOO |
分类号 |
C07D211/14;A61K31/445;A61K31/451;A61P25/18;C07D211/18 |
主分类号 |
C07D211/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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