发明名称 THERAPEUTIC AGENT FOR TREATING MENTAL DISEASE
摘要 PURPOSE: To obtain a curing agent for human psychasthenia having high miscibility to aγ-receptor and useful for curing of a human neurological diseases by containing specific compounds. CONSTITUTION: This curing agent contains a pure optical isomer or a mixture of optical isomers in a free base state or a pharmaceutically allowable acid added salt state of a compound of the formula (R<1> is a halogen or hydroxy; R<2> is H or methyl; R<3> is H or a halogen) in an amount effective for anti- neurological diseases. As the compound of the formula, (±)erythro-α-(4- hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidine ethanol is exemplified. The compound of the formula is used in a formulation of tablet or capsule and within a range of 1-120mg of an active substance by combinedly using with a suitable excipient.
申请公布号 JPH03170428(A) 申请公布日期 1991.07.24
申请号 JP19900308425 申请日期 1990.11.13
申请人 SYNTHELABO SA 发明人 SAROMON ZEDO RANJIE;JIYONATAN FUROSUTO;JIYOAN SUKEEMAKE;BERUNAARU GODEIRIEERU;JIYAN BERUTAN;JIYAN RUSOO
分类号 C07D211/14;A61K31/445;A61K31/451;A61P25/18;C07D211/18 主分类号 C07D211/14
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