| 摘要 |
The invention comprises the monohydrate of the equimolecular complex of ascorbic acid and pyridoxine base. The compound may be prepared by reacting pyridoxine base and ascorbic acid in equimolecular proportions in the presence of at least sufficient water to form the monohydrate. An organic solvent, e.g. ethanol or other alcohol, may be present and the reaction may be carried out at 20 DEG to 60 DEG C. Examples are given. Pharmaceutical compositions comprise the monohydrate of the equimolecular complex of ascorbic acid and pyridoxine base in association with aqueous or non-aqueous diluents, carriers or coatings. |
