摘要 |
<p>(A) Salts of orotic and/or dihydroorotic acid with prim., sec. or tert. aliphatic amines contng. at least 1 other hydrophilic gp., such as OH, esterified OH, COOH, amino or carbamoyl. (B) Pharmaceutical compns. contng. these salts. In geriatrics. Dimethylaminoethanol orotate. Stable and easily form 10-20% solns. in water. The acid and base, in a molar ratio or with an excess of amine, are heated together opt. in the presence of a suitable solvent.</p> |