| 摘要 |
Mandelamidines as hypotensive agents. Compds. 3R1-4R2-C6H3-CHOH-C(:NH)NR3R4 (where R1 and R2 are H, OH, 1-3C alkyl or -alkoxy or R1 + R2 = alkylenedioxy, R3 = H, 1-3C alkyl or Ph, R4 = OH 2-or 3-C-alkyl or Ph, R4 may be H or Me when R2 = OH or 1-3C alkoxy and R1 = H or when R2 = OH and R1 = 1-3C alkoxy or when R1 + R2 = alkylene dioxy) are prepd. by reacting an imino-ester with an amine RR4NH or an amidine with a hydroxylamine.
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