摘要 |
A polypeptide called cartilage-inducing factor B (CIF-B) or transforming growth factor beta 2 (TGF- beta 2) that is found in bone and has heretofore been identified as having in vitro cartilage-inducing activity, TGF- beta activity, and anti-inflammatory activity has now been found to possess potent oncostatic activity. CIF-B showed oncostatic activity on human and animal tumors, including carcinomas, adenocarcinomas, lymphomas, and melanomas. |