Inhibitors for testosterone 5 alpha -reductase activity

摘要

Inhibitors of testosterone 5 alpha -reductase activity, for example those of formula: wherein novel substituents are provided at the R4, R6, R7, R17 alpha and/or R17 beta positions are useful for the treatment of diseases whose progress is aided by activation of androgen receptors, e.g., prostate cancer, benign prostatic hyperplasia, acne, seborrhea, hirsutism, androgenic alopecia and the like.