| 摘要 |
<p>4-Amino-5-chloro-2-methoxy-N-((1-(3-benzylsulfonylpropyl)piperidin-4-yl)methyl)benzamide, its pharmaceutically acceptable salt or its N-oxide compound; medicinal compositions comprising this compound and pharmaceutically acceptable additives; and serotonin 4 receptor antagonists, digestive function improving agents and preventives or remedies for various digestive diseases, each containing the above compound as the active ingredient. Because of having a selectively high affinity for serotonin 4 receptor and showing an agonism thereto, the above compound is useful as a preventive and remedy for various digestive diseases, central nervous system injury, action disorder of heart, urologic diseases, etc. Moreover, it has little toxicity and excellent absorbability.</p> |
