发明名称 Procedure for preparing a crystalline form of the disodium salt of 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl- 4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid
摘要 Procedure for preparing a crystalline form of the disodium salt of 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl- 4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid. Synthetic compound with interesting therapeutic properties, and in the treatment of reversible obstructive diseases of the airways, produced by suspending 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H- pyrano[3,2-g]quinoline-2,8-dicarboxylic acid in an organic solvent, such as isopropanol, acetone, dimethoxyethane, ethanol, acetonitrile, etc., refluxing the solvent used, adding a sodium hydroxide solution, allowing to cool to ambient temperature, and isolating the desired product by the conventional methods. <IMAGE>
申请公布号 ES2021971(A6) 申请公布日期 1991.11.16
申请号 ES19900000728 申请日期 1990.03.12
申请人 INKE, S.A. 发明人 BOSCH ROVIRA ANA;DALMASES BARJOAN PERE;CALDERO GES JOSE MARIA
分类号 A61K31/47;C07D491/052;(IPC1-7):C07D491/052 主分类号 A61K31/47
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