Analyte sensors having a membrane with low temperature sensitivity

摘要

Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a membrane with low temperature sensitivity. The sensing layer is disposed on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.

主权项

1. An analyte sensor comprising:
a first electrode, a second electrode, and a sensing layer; and a membrane disposed on the sensing layer, wherein the membrane comprises a poly(4-vinylpyridine)-co-polystyrene polymer and an epoxide-polyether-epoxide crosslinker of the formula: wherein m, n and o are each independently positive integers, R′ and R″ are each a linking group, and EO is ethylene oxide and PO is propylene oxide.