SYSTEM FOR DETECTING NUCLEIC ACID HYBRIDISATION, PREPARATION METHOD AND APPLICATION THEREOF

摘要

The invention concerns nucleic acid detection using a probe consisting of: a binding domain A, consisting of a single strand polynucleotide; an intermediate domain B, consisting of at least a stop synthon; and a display domain C, consisting of a double strand polynucleotide, wherein is incorporated at least a marked nucleotide constituting detection means. The use of said probes amplifies the hybridisation signal with nucleic acid target sequences.