发明名称 |
NEURAMINIC ACID COMPOUNDS |
摘要 |
[Constitution] A neuraminic acid compound represented by the formula: (see formula 1) [wherein R1 represents a C1-C4 group which may be substituted with a halogen atom; R2, R3 and R4 may be the same or different and each represents a hydrogen at om or a C3-C25 aliphatic acyl group; and W represents a hydrogen atom or an ester residue, provided that the case where R1 is a methyl group and each of R2, R3, R4 and W is a hydrogen atom is excluded] or a pharmacologically acceptable salt thereof. [Effect] The neuraminic acid compound of the present invention exhibits excellent in vivo sialidase inhibitory activity and is useful as a therapeutic agent or a preventive agent for influenza viral infections.
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申请公布号 |
CA2263336(C) |
申请公布日期 |
2007.03.13 |
申请号 |
CA19972263336 |
申请日期 |
1997.08.12 |
申请人 |
SANKYO COMPANY, LIMITED |
发明人 |
YAMASHITA, MAKOTO;HONDA, TAKESHI;KOBAYASHI, YOSHIYUKI |
分类号 |
C07D309/28;A61K31/35;A61K31/351;A61K31/365;A61K31/695;A61P31/16;C07D407/12;C07F7/10 |
主分类号 |
C07D309/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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