摘要 |
Microfluidic devices are disclosed for carrying out cyclic or iterated reactions such as PCR, LDR, and other cyclic or iterated reactions. A microchannel forms a closed loop, through which a reaction mixture may be thermally cycled an arbitrary number of times. Flow is preferably mediated primarily by electrokinetics. Multiple temperature zones may be employed along the course of a single microchannel loop, for example for PCR. Embodiments may be compact, automated, fast, and operable in continuous-flow mode. Real-time reaction monitoring may optionally be used.
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申请人 |
BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE;SOPER, STEVEN, A.;NIKITOPOULOS, DIMITRIS, E.;MURPHY, MICHAEL, C. |
发明人 |
SOPER, STEVEN, A.;NIKITOPOULOS, DIMITRIS, E.;MURPHY, MICHAEL, C. |