NOVEL COMPOUNDS, PROCESS FOR PREPARING THE SAME, AND COMPOSITION COMPRISING THE SAME FOR INHIBITING PAIN

摘要

A compound is provided to suppress effectively chronic neuropathic pain and inflammatory pain by suppressing T-type calcium channel activity. A compound is indicated as a chemical formula 1. In the chemical formula 1: R1 is hydrogen; cycloalkyl of CH2-C3~C10; benzyl substituted or non-substituted to one or more radicals selected from a group consisting of linear or branched alkyl of C1~C10, alkoxy of C1~C4, halogen, nitro and N(CH3)2. In the chemical formula 1: R2 is NR5R6; R3 and R4 are aryl of C6~C20 or aryl of C6~C20 substituted to halogen; R5 and R6 are hydrogen, p- tolyloxy or C6~C20 of aryl; n is integer of 1 to 5.