发明名称 STABLE, LOW VISCOSITY ANTIBODY FORMULATION
摘要 The present invention relates to a stable, low viscosity antibody formulation, wherein the formulation comprises a high concentration of anti-IL6 antibody. In some embodiments, the invention is directed to a stable, low viscosity antibody formulation comprising about 50 mg/mL to about 400 mg/mL of an anti-IL6 antibody, and arginine, wherein the antibody formulation is in an aqueous solution and has a viscosity of less than 20 cP at 23° C. Also provided are methods of making and methods of using such antibody formulations.
申请公布号 HK1211840(A1) 申请公布日期 2016.06.03
申请号 HK20150112690 申请日期 2015.12.24
申请人 MEDIMMUNE LLC 发明人 BEE, JARED J;SANTACROCE, PAUL P;DU, JIALI J;DIMITROVA, MARIANA M
分类号 A61K 主分类号 A61K
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