发明名称 UN PROCEDIMIENTO PARA PREPARAR UNA COMPOSICIËN ANTIBIËTICA DE TETRACICLINA
摘要 <p>Pharmaceutical and veterinary compositions comprise a tetracycline antibiotic (many examples being given) and an adjuvant compound selected from pyromellitic acid; trimellitic acid-1,2-anhydride; rhodizonic acid; disodium 2,3-pyrazine disulphonate; 2-naphthol-8-sulphonic acid; 1 - naphthol - 4 - sulphonic acid; salicylaldehyde; compounds of the general formula <FORM:0905092/VI/1> wherein R1 and R2 are the same and may be hydroxycarboxy lower (C1-6) alkyl or alkyl radicals or R1 is hydroxy and R2 is a hydroxycarboxy lower alkyl, phenyl, xylyl or benzyl radical or R1 is the potassium salt of a hydroxy radical and R2 is the phthalic radical or R1 is hydrogen and R2 is hexahydrohexyl; tri-(2-carboxyethyl) phosphine hydrochloride and bis-(2-carboxyethy) phenyl phosphine oxide and simple salts of these compounds not already in simple salt form and salts with tetracycline compounds. The compositions may be in conventional forms suitable for oral and parenteral administration including mixtures with animal feedstuffs.</p>
申请公布号 ES259408(A1) 申请公布日期 1960.12.16
申请号 ES19080002594 申请日期 1960.07.04
申请人 AMERICAN CYANAMID COMPANY 发明人
分类号 A61K31/65;A61K31/66;C07D307/83;C07D311/40;C07H17/07;(IPC1-7):A61K31/65 主分类号 A61K31/65
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