| 摘要 |
<p>5-Acyl-2,3-dihydrobenzo-furan or -thiopehen-2-carboxylic acids prepn. Cpds. (I) useful as antitussive agents and diuretics: (where R is 2-7C alkyl; X is O or S; Y1 is H, Me or MeO; Y2 is H or Me; Z1 and Z2 are H, Cl, Br or I, Me, Et, MeO or EtO) are prepd. by hydrolysing the corres. 1-10C alkyl or 5-7C cycloalkyl ester formed by a Friedel-Craft reaction on the corres. 5-unsubstd. 2,3-dihydrobenzo-furan or -thiopehen carboxylic acid ester.</p> |
