摘要 |
Novel 1,3-aminoalcohol of the formula WHEREIN N HAS THE VALUE OF 1 TO 4, INCLUSIVE, WHEREIN R', R'', and R''' are hydrogen, halogen, alkyl of 1 to 6 carbon atoms, inclusive, and alkoxy of 1 to 6 carbon atoms, inclusive, or CF3, are prepared. The new compounds of formula IV per se as well as in the form of acid addition salts have diuretic activity and some of them have antihyperglycemic activity. Compounds of formula IV are thus useful to provide diuretics in mammals and are also useful as oral antidiabetic agents.
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