Alkyl and cycloalkylthiophenylalkylaminoalkanols, their salts and the preparation thereof

摘要

Amino-alcohols of the formula <IMAGE> (I) wherein R1 represents either a linear or branched chain alkyl radical having 1 to 4 carbon atoms, or a cycloalkyl radical having 5 or 6 carbon atoms; R2 represents a lower alkyl radical having 1 or 2 carbon atoms; R3 represents a linear or branched chain alkyl radical having 3 to 10 carbon atoms which radical is optionally substituted by phenyl; R4 represents hydrogen, or, together with R3 and the adjacent nitrogen atom, a heterocyclic nucleus of the piperidine type and the corresponding non-toxic salts of said amino-alcohols; preparation of the above and their use as antispasmodic, peripheral vasodilatory and anti-hypertensive agents and as an agent having a protective activity against anoxia of the myocardium.