| 摘要 |
<p>It has been a problem that the known LAL method of endotoxin assay suffers from batch-to-batch differences in sensitivity, does not measure absolute amounts of endotoxin and gives some false positives. The assay of the invention quantitates endotoxin by making use of the binding interaction of the lipopolysaccharide (LPS) component of endotoxin with a polymyxin or octapeptin or a similar cyclic peptide. The cyclic peptide or the LPS is labelled, preferably enzyme-labelled.</p> |
