| 摘要 |
NEW MATERIAL:An alkaloid shown by the formula (R1 to R3 are H or OH). EXAMPLE:2,4,5,6,7-Pentahydroxytetrahydrocyclopenta[6]pyrrolidine. USE:A glucosidase inhibitor. Usable as an antiviral agent, an immunomodulator, a cancer metastasis inhibitor, etc. PREPARATION:JIKOTSUPI, root skin of Lycium chinense MILL of the family Solanaceae, is extracted with water and/or an alcohol, a supernatant liquid obtained after removal of the extracted solution is precipitated by adding ethanol, the supernatant liquid is subjected to column chromatography or high- performance liquid chromatography for collection once or more times, eluted with water, ammonia, acetonitrile, methanol, acetone, etc., as an eluting solvent and fractioned while confirming the objective component by thin layer chromatography. |
