NON HUMAN TRANSGENIC ANIMAL IN WHICH THE EXPRESSION OF THE GENE CODING FOR INSULIN IS DELETED
摘要
The invention concerns the use of a non-human transgenic mammal wherein at least one of the alleles of at least one of two genes coding for endogenous insulin is made functionally inoperative with respect to the expression of insulin for determining medicines acting on pathologies involving insulin.
申请公布号
WO9845422(A1)
申请公布日期
1998.10.15
申请号
WO1998FR00667
申请日期
1998.04.02
申请人
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE);JAMI, JACQUES;BUCCHINI, DANIELLE;JOSHI, RAJIV, LOCHAN