发明名称 |
Method for the treatment of retinopathy of prematurity and related retinopathic diseases |
摘要 |
<p>The present invention provides the use of cells from a vasculotrophic lineage negative hematopoietic stem cell population for the preparation of a pharmaceutical composition for treating a mammal suffering from or at risk of developing retinopathy of prematurity or a related retinopathic disease wherein the cells are transfected with a therapeutically useful gene encoding for an angiostatic fragment of Trp-RS and wherein the pharmaceutical composition is for administering to the retina of the mammal an amount of cells from a vasculotrophic lineage negative hematopoietic stem cell population effective to promote beneficial physiological revascularization of damaged areas of the retina and to ameliorate damage to the retina caused by the disease.</p> |
申请公布号 |
AU2006216473(A1) |
申请公布日期 |
2006.08.31 |
申请号 |
AU20060216473 |
申请日期 |
2006.02.24 |
申请人 |
THE SCRIPPS RESEARCH INSTITUTE |
发明人 |
EDITH AGUILAR;EYAL BANIN;MARTIN FRIEDLANDER |
分类号 |
A61K31/137;C12N5/0789 |
主分类号 |
A61K31/137 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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