INTERFERANT ELIMINATING BIOSENSORS

摘要

Interferant eliminating analyte sensors and sensing process prevent erroneous assays. Glucose electrodes were coated with an oxidizing enzyme (peroxidase) which allows hydrogen peroxide to selectively oxidize ascorbate, urate, bilirubin, and acetaminophenol in the presence of glucose. Hydrogen peroxide may be added to the assayed solution or generated in situ. The oxidizing enzyme was prevented from causing undesired reduction currents at the glucose electrode by preventing contact of the oxidizing enzyme with the glucose electrode, or by increasing the applied voltage. 28