发明名称 |
Process for purifying coagulation factor VIII using DEAE-crosslinked dextran |
摘要 |
A process for purifying coagulation factor VIII which comprises contacting a plasma or a plasma fraction containing prothrombin complex and coagulation factor VIII (antihemophilic factor A) with diethylaminoethyl-crosslinked dextran to adsorb and remove the prothrombin complex from said plasma or plasma fraction. Coagulation factor VIII thus obtained can be administered to control the bleeding in hemophilia A patients.
|
申请公布号 |
US4093608(A) |
申请公布日期 |
1978.06.06 |
申请号 |
US19770783625 |
申请日期 |
1977.04.01 |
申请人 |
THE GREEN CROSS CORPORATION |
发明人 |
IGA, YOSHIRO;SHIGA, MASASHI |
分类号 |
C07K14/745;A61K35/14;A61K38/00;A61K38/16;C07K14/00;C07K14/755;(IPC1-7):C07G7/00 |
主分类号 |
C07K14/745 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|