INSULIN PRECURSOR AND ITS PRODUCTION

摘要

Human insulin precursors of the general formula B(1-29)-Xn-Y-A(1-21) II wherein Xn is a peptide chain with n naturally occurring amino acid residues, n = 0 - 33, Y is Lys or Arg, B(1-29) is a shortened B-chain of human insulin from Phe<B1> to Lys<B29> and A(1-21) is the A chain of human insulin, with the proviso that the peptide chain -Xn-Y- does not contain two adjacent, basic amino acid residues.