发明名称 |
High efficiency mammalian gene expression vectors that contain exogenous promoter and entire 5' untranslated region in the upstream from start codon for inherent gene as transcription regulatory site |
摘要 |
The present invention relates to the highly efficient eukaryotic expression vectors which have regulatory sequences derived from human cytomegalovirus immediate early gene or human EF1 alpha gene, thereof transcriptional regulatory regions contain exogenous promoter and entire 5' untranslated region correspond to the condition of inherent gene expression. Therefore, the eukaryotic expression vectors provided in accordance with the present invention can drive high levels of gene expression in human and animal cells and have utilities as gene therapy agent. |
申请公布号 |
AU1896500(A) |
申请公布日期 |
2000.07.24 |
申请号 |
AU20000018965 |
申请日期 |
1999.12.31 |
申请人 |
VIROMED LIMITED |
发明人 |
SUN-YOUNG KIM;YOUNG JOO LEE;SEUNG SHIN YU;DUK-KYUNG KIM |
分类号 |
C12N15/09;A61K38/19;A61K48/00;A61P9/10;C12N1/21;C12N15/79;C12N15/85 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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