HETEROPOLYCYCLIC COMPOUNDS AND THEIR USE AS ANTAGONISTS OF METABOTROPIC GLUTAMATE RECEPTOR

摘要

Compounds of formula wherein X, Y and Z are independently selected from the group consisting of N, O, S, C and CO wherein at least one X, Y and Z is heteroatom; Ar1 and Ar2 are independently selected from the group consisting of a heterocyclic or fused heterocyclic moiety and an aromatic moiety; acts as antagonist at metabotropic glutamate receptor, and are useful for treating neurological diseases and disorders.