System and method to regulate ultrafiltration

摘要

A medical device system including a physiological sensor and ultrafiltration unit senses a physiological signal in a patient and computes a fluid status measurement of the patient using the physiological signal. Ultrafiltration therapy is delivered to the patient according to a therapy delivery control parameter established in response to the fluid status measurement.

主权项

1. A medical monitoring system, comprising:
an implantable medical device comprising one or more sensors for sensing at least two different physiological signals in a patient; a processor configured to receive the physiological signals and compute at least two different fluid status measurements of the patient using each of the at least two different physiological signals; wherein at least one of the physiological signals is an ECG signal; an external therapy delivery device for delivering ultrafiltration therapy to the patient according to a therapy delivery control parameter; and a controller configured to receive the at least two different fluid status measurements and establish a setting for the control parameter in response to the fluid status measurements; a memory storing a target range of the fluid status measurements, wherein the target range is an index computed using a combination of the at least two different fluid status measurements; the controller further configured to compare each of the fluid status measurements to the target range and automatically establish the control parameter in response to the comparison that readjusts an ultrafiltration level or an ultrafiltration pump flow rate.