发明名称 |
EMULSIONS OR MICROEMULSIONS FOR USE IN ENDOSCOPIC MUCOSAL RESECTIONING AND/OR ENDOSCOPIC SUBMUCOSAL DISSECTION |
摘要 |
The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection. |
申请公布号 |
US2016256594(A1) |
申请公布日期 |
2016.09.08 |
申请号 |
US201615154857 |
申请日期 |
2016.05.13 |
申请人 |
COSMO TECHNOLOGIES LTD. |
发明人 |
MORO Luigi;LONGO Luigi Maria;FRIMONTI Enrico;REPICI Alessandro |
分类号 |
A61L24/04;A61L24/00 |
主分类号 |
A61L24/04 |
代理机构 |
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代理人 |
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主权项 |
1. A pharmaceutical composition in the form of an emulsion or a microemulsion comprising:
(a) an aqueous phase; (b) an oily phase; (c) at least one surfactant; (d) at least one of poloxamer 188, poloxamer 407 or a mixture of poloxamer 188 and poloxamer 407; and (e) at least one physiologically acceptable excipient; wherein said at least one of poloxamer 188, polyoxamer 407 or a mixture of poloxamer 188 and poloxamer 407 is present in an amount below the critical gelation concentration (CGC), and wherein said composition remains in liquid phase at a temperature between about 5° C. and about 40° C. in vitro. |
地址 |
Dublin 2 IE |