<p>A solid oral dosage form comprising diltiazem (or a pharmaceutically acceptable salt thereof) in controlled release form and hydrochlorothiazide in normal release form. Preferably the controlled release component comprises a plurality of spheroids comprising diltiazem and a spheronising agent.</p>
申请公布号
CA2075355(A1)
申请公布日期
1993.02.13
申请号
CA19922075355
申请日期
1992.08.05
申请人
EUROCELTIQUE S.A.
发明人
BUXTON, IAN R.;BROWN, ADRIAN;CRITCHLEY, HELEN;LESLIE, STEWART T.;MALKOWSKA, SANDRA T. A.;PRATER, DEREK A.;MILLER, RONALD B.