Adenosines of formula (I):- where R1 is 1-6C alkyl, and R2 is Me or (if R1 Me) H, effect the heart and circulating systems, and influence lipid transfer. Cpds. (I) may be prepd. by reaction of the corresponding 6-halor or mercapto-purineriboside with an amine of formula R1R2 MeCNH2, with appropriate protection of th OH gps.
