发明名称 |
Lipid-lowering aryloxy(thio)alkanoic acidderivs |
摘要 |
<p>Lipid-lowering aryloxy(thio)alkanoic acid derivs. Title cpds. have the formula (I): (where R1 is 1-14C alkyl or 5-7C cycloalkyl; R2 is H or Me; R3 is OH, OM where M is an alkali or alk. earth metal, 1-3C alkoxy or amino; X and Y are O or S). A pref. cpd. is 2-(6,7,8,9-tetrahydro-dibenzofuran-2-yloxy)-octanoic acid and its alkali(ne earth)metal salts. Cpds. lower lipid and cholesterol levels with only a slight tendency to hepatomegaly.</p> |
申请公布号 |
CH530388(A) |
申请公布日期 |
1972.11.15 |
申请号 |
CH19720012239 |
申请日期 |
1970.03.20 |
申请人 |
CIBA-GEIGY AG |
发明人 |
FREI,JOERG,DR.;MOREL,CHARLES,DR.;WACKER,OSKAR,DR. |
分类号 |
C07D307/77;A61K31/34;A61K31/38;C07C45/70;C07C49/753;C07D307/91;C07D333/50;C07D333/56;C07D333/76;(IPC1-7):C07D5/16;C07D63/18 |
主分类号 |
C07D307/77 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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