摘要 |
Novel imidazole derivatives of the formula: <IMAGE> wherein R1 is lower alkyl or, phenyl-C1-2alkyl which may be substituted with halogen or nitro; R2 is lower alkyl, cycloalkyl or, phenyl which may be substituted with halogen, lower alkyl, lower alkoxyl or di(lower alkyl)amino, one of R3 and R4 is of the formula: -(CH2)n-COR5 in the formula R5 is amino, lower alkoxyl or hydroxyl and n is integer of 0, 1 or 2, and the other is hydrogen or halogen; provided that R1 is lower alkyl or phenethyl when R3 is halogen, n is 1 and R5 is lower alkoxyl or hydroxyl, and their salts have hypotensive activity.
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