| 发明名称 |
IMPROVED 7-CHLOROQUINALDINE SYNTHESIS |
| 摘要 |
An improved process is described which utilizes tetrachloro-1,4(or 1,2)-quinone as an oxidant in the Doebner-Miller synthesis of 7-chloroquinaldine, a starting material in the preparation of leukotriene antagonists. The process improves yield and eliminates the need of forming a ZnC1 2 complex to isolate the end product.
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| 申请公布号 |
CA2080406(A1) |
申请公布日期 |
1993.04.18 |
| 申请号 |
CA19922080406 |
申请日期 |
1992.10.13 |
| 申请人 |
SONG, ZHIGUO;HUGHES, DAVID L. |
发明人 |
SONG, ZHIGUO;HUGHES, DAVID L. |
| 分类号 |
C07B61/00;C07D215/18;C07D215/50;C07D217/02;(IPC1-7):C07D215/18 |
主分类号 |
C07B61/00 |
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