| 发明名称 |
FSH-RELEASING PEPTIDE |
| 摘要 |
FSH-RELEASING PEPTIDE A 28,000-dalton protein with FSH-releasing activity is isolated from porcine follicular fluid in a multi-step procedure including gel filtration, ion exchange chromatography and several reverse-phase high-performance liquid chromatography steps. The 28 kD protein promotes secretion of FSH, but not of LH, in a rat anterior pituitary monolayer culture system, exhibiting an EC50 of 0-5 ng/ml. |
| 申请公布号 |
CA1302651(C) |
申请公布日期 |
1992.06.02 |
| 申请号 |
CA19870533215 |
申请日期 |
1987.03.27 |
| 申请人 |
SALK INSTITUTE FOR BIOLOGICAL STUDIES (THE) |
发明人 |
VALE, WYLIE W., JR.;RIVIER, JEAN E.F.;SPIESS, JOACHIM |
| 分类号 |
C12P21/02;A61K38/00;A61K38/04;A61P13/02;A61P15/00;C07K1/20;C07K14/00;C07K14/435;C07K14/52;C07K14/575 |
主分类号 |
C12P21/02 |
| 代理机构 |
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代理人 |
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| 地址 |
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