| 发明名称 |
RADIOLABELED ANTI-PLATELET MONOCLONAL ANTIBODY FOR IMAGING IN-VIVO THROMBI |
| 摘要 |
There is provided a radiolabeled monoclonal antibody of the class IgG1 which reacts readily with both normal human and dog blood platelets while failing to react with thrombasthenic human platelets. This antibody has the property of completely blocking interaction of fibrinogen with platelets induced by ADP, and the ability to detect fresh thrombi in vivo.
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| 申请公布号 |
CA1333264(C) |
申请公布日期 |
1994.11.29 |
| 申请号 |
CA19860509241 |
申请日期 |
1986.05.15 |
| 申请人 |
RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (THE) |
发明人 |
SRIVASTAVA, SURESH C.;COLLER, BARRY S.;MEINKEN, GEORGE E. |
| 分类号 |
G01N33/534;A61K38/00;A61K51/10;C07K1/113;C07K14/005;C07K14/195;C07K16/00;C07K16/28;C12N5/10;C12N15/02;C12P21/08;C12R1/91;G01N33/53;G01N33/577;(IPC1-7):C07K15/28;A61K49/02 |
主分类号 |
G01N33/534 |
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