发明名称 |
Phenyl alkyl ketone substituted by cyclic amine and a process for the preparation thereof. |
摘要 |
A process for the production of cyclic amine substituted phenyl-alkyl ketone compounds comprises aminolysis of a p-halophenylalkyl ketone with a cyclic amine in water at at least 130[deg]C. A process for the production of cyclic amine substituted phenyl-alkyl ketone compounds (I) of formula (1) comprises aminolysis of a p-halophenylalkyl ketone of formula (2) with a cyclic amine of formula (3) in water at at least 130[deg]C. [Image] [Image] R 1, R 2optionally substituted 3-20C alkylene optionally containing at least one -O-, -S- or -N(R 4); R 3optionally substituted 2-20C alkyl; R 41-3C alkyl, 3-5C alkenyl, 7-9C phenalkyl, 1-4C hydroxyalkyl or phenyl; X : halo. |
申请公布号 |
ZA9703797(B) |
申请公布日期 |
1997.12.01 |
申请号 |
ZA19970003797 |
申请日期 |
1997.05.02 |
申请人 |
CIBA SPECIALTY CHEMICALS HOLDING INC. |
发明人 |
RINALDO HUSLER;RUDOLF SCHWABE;RETO LUISOLI |
分类号 |
C07D295/10;C07D211/14;C07D241/04;C07D265/28;C07D265/30;C07D295/112;C07D295/12;C07D295/135;C08F2/50;G03F7/028;G03F7/031 |
主分类号 |
C07D295/10 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|