| 发明名称 |
SELECTIVE EPOXIDATION PROCESS FOR PREPARING PHARMACEUTICAL COMPOUNDS |
| 摘要 |
Cryptophycin compounds possessing a .beta.-epoxy moiety may be made with high stereoselectivity at various steps in the overall synthetic process. This invention also provides novel intermediates useful in preparing Cryptophycin compounds. |
| 申请公布号 |
CA2281104(A1) |
申请公布日期 |
1998.09.03 |
| 申请号 |
CA19982281104 |
申请日期 |
1998.02.25 |
| 申请人 |
ELI LILLY AND COMPANY;UNIVERSITY OF HAWAII;WAYNE STATE UNIVERSITY |
发明人 |
HOARD, DAVID WARREN;MOHER, ERIC DAVID;PATEL, VINOD FRANCIS;NORMAN, BRYAN HURST |
| 分类号 |
C07D303/16;A61K31/395;A61P35/00;C07C229/08;C07C271/22;C07D233/54;C07D277/30;C07D301/03;C07D303/38;C07D303/40;C07D303/46;C07D405/06;C07D405/12;C07D413/06;C07F7/18 |
主分类号 |
C07D303/16 |
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