| 摘要 |
PCT No. PCT/EP94/03652 Sec. 371 Date May 3, 1996 Sec. 102(e) Date May 3, 1996 PCT Filed Nov. 3, 1994 PCT Pub. No. WO95/12683 PCT Pub. Date May 11, 1995Microbial strains capable of producing enhanced levels of sphingosine, dihydrosphingosine, phytosphingosine and/or derivatives thereof are disclosed. Additionally, there are disclosed methods based on mutagenesis, or other selection techniques, whereby such strains can be produced. As a preferred example thereof, mutant strains of Pichia are provided that are capable of producing about 50% more of such compounds than wild type strains.
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