发明名称 METHOD OF PREDICTING SKIN SPOT FORMATION AND METHOD OF SCREENING SKIN SPOT FORMATION INHIBITOR WITH THE USE OF SPOT SITE-INCREASING GENES AS INDICATION
摘要 The present invention provides a skin test method for predicting the formation of spots in the skin. This method is characterized by judging skin to be susceptible to spot formation in the case expression of genes consisting of MLSTD1, MOGAT1, FADS2, FADS1, HSD3B1, ELOVL3, BG1, PECR, FABP7, FA2H, HAO2, ALOX15B, PDE6A, LZTS1, SEC14L4, BAMBI, CIDEA, TERE1, GAL, THRSP, INSIG1 or CUTL2 in the epidermis is accelerated, or the expression of genes consisting of RBBP6, MSMB, WIF1, ANKRD12, FLG, SYNE2, SCEL, NKTR or AMBP in the epidermis is decreased as compared with normal expression in the epidermis.
申请公布号 EP2011883(A4) 申请公布日期 2010.02.10
申请号 EP20070742776 申请日期 2007.04.24
申请人 SHISEIDO COMPANY, LIMITED 发明人 AOKI, HIROFUMI;KISHIMOTO, JIRO;MORO, OSAMU
分类号 C12Q1/68;A61K45/00;A61P17/16;C12N15/09;G01N33/15;G01N33/50 主分类号 C12Q1/68
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