| 发明名称 |
PROCESS FOR THE PREPARATION OF MACROLIDE COMPOUNDS |
| 摘要 |
A process is described for preparing a compound (I) <CHEM> (wherein R<1> represents a methyl, ethyl or isopropyl group and OR<2> represents a hydroxy, methoxy or acetyloxy group) which comprises reducing a compound (II) <CHEM> (wherein R<1> is as defined above, R<3> is a hydrogen atom, a methyl group or a protecting group and Hal represents a halogen atom. The intermediates (II) are new compounds. |
| 申请公布号 |
EP0307221(B1) |
申请公布日期 |
1993.06.02 |
| 申请号 |
EP19880308345 |
申请日期 |
1988.09.09 |
| 申请人 |
AMERICAN CYANAMID COMPANY |
发明人 |
RAMSAY, MICHAEL V. J.;FREEMAN, STEPHEN;SHINGLER, ANTHONY H.;PEREIRA, OSWY Z.;DOLAN, SIMON C. |
| 分类号 |
C07D493/22;A61K31/365;A61P31/04;A61P33/00;C07H19/01 |
主分类号 |
C07D493/22 |
| 代理机构 |
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代理人 |
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| 主权项 |
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