发明名称 |
ASYMMETRIC LIGANDS USEFUL FOR TRANSITION METAL CATALYZED BOND FORMING REACTIONS |
摘要 |
Ligands useful for transition metal catalyzed bond forming reactions are provided with a metal binding portion having at least one metal binding moiety (I), wherein Ar and Ar' each is an aryl or a heteroaryl. These ligands may be prepared by providing an aromatic carboxylic acid having a diarylphosphino or diheteroarylphosphino substituent on the aromatic ring, and forming an ester or an amide derivative of the carboxylic acid by coupling with a chiral diol or a chiral diamine. The ligands facilitate flexible strategies for enantiocontrolled construction of five membered carbocyclic rings with varying substitution patterns and high enantioselectivity. |
申请公布号 |
WO9312260(A2) |
申请公布日期 |
1993.06.24 |
申请号 |
WO1992US10386 |
申请日期 |
1992.12.02 |
申请人 |
BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIO |
发明人 |
TROST, BARRY, M.;VAN VRANKEN, DAVID, L. |
分类号 |
B01J31/24;C07D207/40;C07D207/416;C07F9/50;C07F9/553;C07F9/655;C22B3/38 |
主分类号 |
B01J31/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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