| 发明名称 |
DIASTEREOSELECTIVE HYDROGENATION OF FOLIC ACID TO TETRAHYDROFOLIC ACID |
| 摘要 |
O.Z. 0050/42948 A method for the diastereoselective hydrogenation of folic acid to tetrahydrofolic acid, comprises carrying out the hydrogenation of the folic acid in the presence of an immobilized rhodium(I) complex of an optically active diphosphine in a neutral aqueous buffer solution under an H2 pressure of more than 20 bar and at a temperature exceeding 60.degree.C.
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| 申请公布号 |
CA2086911(A1) |
申请公布日期 |
1993.07.17 |
| 申请号 |
CA19932086911 |
申请日期 |
1993.01.07 |
| 申请人 |
BRUNNER, HENRI;HUBER, CHRISTIAN;BUBLAK, PETRA |
发明人 |
BRUNNER, HENRI;HUBER, CHRISTIAN;BUBLAK, PETRA |
| 分类号 |
B01J31/24;C07B61/00;C07D475/04;(IPC1-7):C07D475/04 |
主分类号 |
B01J31/24 |
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