Verfahren zur Herstellung von 2,2-Dialkyl-3-acyloxy-propanalen

摘要

1326717 2,2 - dialkyl - 3 - acyloxypropanols BADISCHE ANILIN- & SODAFABRIK AG 6 Jan 1971 [7 Jan 1970] 576/71 Heading C2C 2,2 - dialkyl - 3 - acyloxypropanols of general formula where R1 denotes hydrogen or an aliphatic, cycloaliphatic, araliphatic or aromatic radical and R2 and R3 separately denote identical or different aliphatic radicals or jointly with the adjacent carbon atom from a cycloaliphatic ring, are prepared by reacting a carboxylic acid R1COOH with formaldehyde and a secondary aldehyde in the presence of a strong acid while removing water formed and present at the beginning of the reaction. The formaldehyde may be added as paraformaldehyde, trioxan or in the form of an aqueous formaldehyde solution and a solvent forming an azeotrope with water may be used. Many starting materials are listed and the acid catalysts may be trichloracetic, phosphoric, cyanoacetic, o-bromobenzoic, p-chlorobenzoic, benzene and p-toluenesulphonic, sulphuric and phosphoric acids. Examples describe the preparation of acetoxypivaldehyde, tri-, di- and mono-chloroacetoxypivaldehyde, αα-dichloropropionyloxy-pivaldehyde, isobutyryloxypivaldehyde, 2 - methyl- 2 - n - propyl - 3 - acetoxypropanol, 2 - ethyl- 2 - n - butyl - 3 - acetoxypropanal, 1- acetoxymethyl hexahydrobenzaldehyde, benzoyloxypivaldehyde, and 3-4- and 2-4-dichlorobenzoyloxypivaldehyde.