发明名称 (OMEGA-PIPERAZINYLALKOXY)POLYALKOXYBENZENE DERIVATIVE AND ITS ACID ADDITION SALT
摘要 NEW MATERIAL:An (omega-piperazinylalkoxy)polyalkoxybenzene derivative shown by the formulaI(m is 2 or 3; n is 3 or 4; R<1> is 1-3C alkyl; R<2> is pyridyl, pyrazinyl, pyrimidyl, or phenyl which may be replaced with halogen, trifluoromethyl, alkoxy, or alkyl) and its acid addition salt. EXAMPLE:1-[3-(4-Phenyl-1-piperazinyl)propoxy]-3,4-dimethoxy-benzene. USE:A hypotensor. Quickly showing medicinal effect and durable action. Low acute toxicity. PROCESS:A halogenoalkoxypolyalkoxybenzene shown by the formula II (X is halogen) is reacted with a piperazine derivative shown by the formula III, to give a compound shown by the formulaI.
申请公布号 JPS5824563(A) 申请公布日期 1983.02.14
申请号 JP19810122301 申请日期 1981.08.04
申请人 MITSUBISHI KASEI KOGYO KK 发明人 KIKUMOTO RIYOUJI;FUKAMI JIICHI;NAKAO KENICHIROU;SUGANO MAMORU
分类号 C07D295/06;A61K31/44;A61K31/4402;A61K31/495;A61K31/505;A61P9/12;C07D213/74;C07D239/42;C07D241/20;C07D295/08 主分类号 C07D295/06
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