发明名称 |
6,7,8,9-Tetrahydronaphtho(1,2-B)furan-8-amine derivatives and their use as dopamine receptor stimulants |
摘要 |
Herein is disclosed compounds of the formula <IMAGE> in which R1 and R2 each is hydrogen or lower alkyl or R1 and R2 together form an alkylene of the formula (CH2)n wherein n is an integer from 4 to 6, therapeutically acceptable acid addition salts thereof, processes for their preparation, methods of using the compounds and pharmaceutical compositions. The compounds exhibit dopamine-receptor stimulating activity in a mammal and are useful for treating hyperprolactinemia, galactorrhea, amenorrhea, impotence, Parkinsonism, diabetes, acromegaly, hypertension and other central nervous system disorders.
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申请公布号 |
US4470990(A) |
申请公布日期 |
1984.09.11 |
申请号 |
US19830474757 |
申请日期 |
1983.03.14 |
申请人 |
AYERST, MCKENNA & HARRISON INC. |
发明人 |
ASSELIN, ANDRE A.;HUMBER, LESLIE G. |
分类号 |
C07D307/92;(IPC1-7):A61K31/34 |
主分类号 |
C07D307/92 |
代理机构 |
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地址 |
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